产品货号：
Z35872
中文名称：
PON1抗体
英文名称：
Anti-PON1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PON1 Antibody |
| 指标别名 | A esterase 1;Aromatic esterase 1;ESA;K 45;paraoxonase 1;PON;PON 1;PON1;Serum aryldialkylphosphatase 1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IP |
| 基因名称 | PON1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human PON1 Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides.Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones,and a number of aromatic carboxylic acid esters.Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation. |
| 实际分子量 | 40KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Serum paraoxonase/arylesterase 1(PON1),also known as aromatic esterase 1,is an enzyme that in humans is encoded by the PON1 gene.It is mapped to 7q21.3.This gene has esterase and more specifically paraoxonase activity.PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses.Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme.PON1(paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein(HDL).The PON1 gene is activated by PPAR-gamma,which increases synthesis and release of paraoxonase 1 enzyme from the liver,reducing atherosclerosis. |
| Uniprot ID | P27169 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunocoprecipitation 1:20 |
相关搜索：PON1抗体，PON1单抗，Anti-PON1 Antibody